Rheumatoid Arthritis Factor Results

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I have rheumatoid arthritis. What is my prognosis?

This article describes some of the prognostic factors used to guide experts arthritis, when treating patients with rheumatoid arthritis.

Evidence suggests there is a narrow window opportunity, perhaps as thin as three months, in which aggressive treatment with disease-modifying anti-rheumatic drugs may reduce X-ray damage and subsequent disability.

Once the diagnosis of rheumatoid arthritis have been made, it is important to recognize patients who are at high risk of rapid progression of disease.

This includes patients who have multiple swollen joints, basic X-ray damage, positivity of rheumatoid factor in blood, and positive results for anti-CCP.

Patients with a worse prognosis may also have functional impairment (inability to perform activities of daily living), the elevation of sedimentation rate (ESR), and protein C-reactive protein (CRP).

Joint destruction may occur early and progresses if not controlled immediately.

The Smoking is a known risk factor for developing rheumatoid arthritis. His role in the progression of the disease is still unknown.

Factors poor prognosis suggest that a patient may have the illness increasingly desperate and harmful. It may also be a greater resistance to therapy with less risk of early drug response. The identification of this subset of patients is important because these patients should be treated more aggressively.

Hopefully, with new research on biomarkers (biological identifiers like illness), it may be possible to adapt personalized treatment most likely to achieve remission in a patient given early. Genetic markers of the disease may also be useful stratification of patients in the future.

It should be noted that disease progression has taken a back seat to the goal to achieve remission. Remission is defined as the absence of disease. However, there is a difference between remission and cure. Discount can be achieved with medication, but medication can be continued. This is different from the healing (or complete remission) where medications can be discontinued and the patient remains free of disease. future articles will discuss this concept further.

Early diagnosis aggressive and early treatment can mean the difference between achieving remission compared to the development of severe deformity and crippling due with rheumatoid arthritis. Initial assessment by a rheumatologist is mandatory.

About the Author

Nathan Wei, MD, FACP, FACR is a rheumatologist and Director of the Arthritis and Osteoporosis Center of Maryland. For more info:
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