what are the malfunction of lysosomes in: a)rehumatoid arthritis b)Tay-Sachs disease?
In Rheumatooid arthritis lysosomes fail to produce lysosomal enzymes so the urate crystals absorbed by macrophages fail to lyse ,so topy is present.
In case of tachy sachs : mutations on chromosome 15 in the HEXA gene encoding the alpha-subunit of the lysosomal enzyme beta-N-acetylhexosaminidase
My [...]